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What is IGF-1 & What Does It Do?
IGF-1 is one of the bioactive components in Velvet Antler (available at the links on left)

First a word about HGH 

Human Growth Hormone. HGH is produced and secreted by the pituitary gland. It peaks at adolescence and at age 60 decreases to about 25 % of the levels at 20 years old. It enters the liver and is converted into IGF-1. IGF-1 is the primary beneficial factor derived from HGH.

HGH is usually administered by injection and can result in harmful side effects. Once you begin HGH therapy, you need to continue to avoid a rapid decline in your condition.

Insulin-like Growth Factor-1 (IGF-1), a natural anabolic growth factor, is only one of a few Growth Factors found in Velvet Antler. Growth Factors consist of peptides (small proteins) which stimulate nuclear DNA to create new proteins.

The following Growth Factors have been identified in Velvet Antler:

IGF-1 - promotes proliferation of many cell types, IGF-I (originally called somatomedin C) is a growth factor structurally related to insulin. IGF-I is the primary protein involved in responses of cells to growth hormone (GH): that is, IGF-I is produced in response to GH and then induces subsequent cellular activities, particularly on bone growth. It promotes tissue growth, organ health, and healthy blood sugar levels.

Unfortunately, IGF-1 blood levels decrease after the age of thirty, similar to decreases in human growth hormone (HGH). As we age and less Growth Hormone is released from the pituitary gland, there is a corresponding drop in IGF-1 levels, yet the body’s demand for IGF-1 does not decrease. As IGF-1 levels decline, the vitality and physical exuberance of youth recedes, further contributing to the process and experience of aging.

IGF-I is mainly secreted by the liver as a result of stimulation by Human Growth Hormone (hGH). Almost every cell in the human body is affected by IGF-I, especially cells in muscle, cartilage, bone, liver, kidney, nerves, skin, and lungs. In addition to the insulin-like effects, IGF-I can also regulate cell growth and development, especially in nerve cells, as well as cellular DNA synthesis.

IGF-1:

  • Stimulates muscle growth and has been shown to benefit the heart (a muscle).
  • Encourages the absorption of Chondroitin Sulfate and Glucosamine Sulfate (also found in Velvet Antler).
  • Regenerates nerve tissue
  • Helps burn fat, increase protein transport into cells, and reduce protein breakdown
  • Improves the production of white blood cells
  • Decreases LDL Cholesterol
  • Improves parathyroid Vitamin D interaction to produce dense bone matrix

IGF-2 - promotes proliferation of many cell types primarily of fetal origin. IGF-2 is almost exclusively expressed in embryonic and neonatal tissues. Following birth, the level of detectable IGF-2 protein falls significantly. While IGF-2 may be primarily fetal in action it is also essential for development and function of organs such as the brain, liver and kidney. It also promotes tissue growth. IGF-2 is secreted by the brain, kidney, pancreas and kidney in mammals. It is more specific in action than IGF-1.

TGF beta (transforming growth factor beta) – breast cancer research; stimulates significant collagen and elastin production, as well as giving supplemental support to healing factors enabling wounds to heal markedly faster. Anti-inflammatory factors also appear to be beneficially effected. Collective scientific opinion views TGF Beta as a major tool in helping to reverse the visible signs of aging.

EPO (erythropoietin) – red blood cell growth stimulant, stimulates stem cells in the bone marrow to increase production of erythrocytes (red blood cells). Used to treat AIDS, HIV, Cancer, and anemia.

NT-3 – neurotrophin (nerve growth factor), stimulates the growth of nerve fibers. Used to treat spinal chord injuries.

BMP-4 (bone morphogenic protein) – induces bone and cartilage formation. Used in spine fusion and the treatment of Osteoporosis

FGF-8 (fibroblast growth factor 8) – essential for development of the skeletal system and nervous system in mammals. Helps nourish nerve cells of both the peripheral and central nervous system., wound healing, and tissue growth.

Luteinizing Hormone Stimulant – stimulates the production of LH (Luteinizing hormone), also called interstitial-cell stimulating hormone (ICSH) and is one of two gonadotropic hormones (hormones which regulates the gonads - sex glands)

LH is produced by the pituitary gland and is a glycoprotein, operating in conjunction with follicle-stimulating hormone (FSH).

In females LH promotes the transformation of the graafian follicle (a small egg-containing vesicle in the ovary) into the corpus luteum, an endocrine gland that secretes progesterone.

In males LH acts on Leydig cells of testes to increase testosterone synthesis and release and increases interstitial cell development

EGF (epidermal growth factor) – negative growth effects on certain carcinomas and accelerates cell growth and wound healing. Used in treatment of cancer and ulcerative colitis.  

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

  

 

 

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